REUSECOV 2
In the first place, within work package 1 (development at laboratory scale of a coating with easy-cleaning properties that facilitates and makes safer medical-surgical instrument reuse), the formulation of a bicomponent solution with easy-cleaning characteristics that can adhere to both plastic and metal substrates has been optimised. On the other hand, in work package 2 (biological evolution of the candidate coating as a healthcare product), the biocompatibility of the chosen coating has been evaluated. In polycarbonate specimen tubes coated with the chosen formula, studies were carried out of: in vitro cytotoxicity (CCL-1 and V79), sensitivity (in vitro skin irritation and rat sensitivity), intracutaneous reactivity in rabbits, acute toxicity in rats and hemocompatibility (erythrocyte agglutination and hemolysis).